Description
- Zolkin is a unique toxin binder which can be added to feed of large animals in small quantities in order to remove mycotoxins, resulting in reduction of liver injury and prevention of mycotoxins from entering the bloodstream
- Zolkin has the ability to get rid of all types of toxins (adsorb and degrade them especially Aflatoxins, Ochratoxin and Fusariotoxins), phytotoxins and poisonous chemicals onto its surface, preventing their absorption from the gastrointestinal tract and consequently preventing their entering to the blood circulation
- Zolkin reduces harmful effects of mycotoxins on liver and subsequently on other vital organs in the animal body due to its strong antioxidant effect which enables it to act as a superoxide anion scavenger as most of the mycotoxins, e.g. aflatoxin B1 (AFB1), T-2 toxin and ochratoxin, provoke oxygen free radical formation. This important role leads to transport of fatty acids into mitochondria for β-oxidation and thus to the decrease of lipid usage and protection of the cell membrane against toxic reactive oxygen species (ROS) and other free radicals which induce membrane damage and mitochondrial structure destruction of hepatocytes and decrease liver metabolism leading to stop apoptosis and necrosis of hepatocytes and also liver injury
- Zolkin enhances detoxification functions of liver and kidney and protects them from harmful effect of mycotoxins, it also reduces liver injury because it can considerably reduce elevation of interleukins levels in cases of induced liver injury, downregulating over-expression of inflammatory cytokines, and reducing the inflammatory response, as toxins can specifically bind to liver macrophages, transmit cell signals and irritate cells to generate a sea of inflammatory cytokines, resulting in pathological changes in the liver
- Zolkin works with a strategy based on competitive inhibition among beneficial and pathogenic organisms in the rumen of large animals resulting in increase of growth rate and improved milk and meat production and quality
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